Record Display for the EPA National Library Catalog
RECORD NUMBER: 45 OF 64
|OLS Field Name||OLS Field Data|
|Main Title||Measurement of Blood Cholinesterase Activity in Laboratory Animals Utilizing Dimethylbutyl Acetate as a Substrate.|
|Author||Cranmer, Morris F. ; Peoples., Anita J. ;|
|CORP Author||Environmental Protection Agency, Perrine, Fla. Perrine Primate Lab.|
|Report Number||found in PB-280 889|
|Stock Number||PB-280 902, found in PB-280 889|
|Additional Subjects||Cholinesterase ; Pesticides ; Toxicology ; Enzymes ; Acetic acid ; Activity ; Laboratory animals ; Experimental data ; Monkeys ; Dogs ; Rats ; Mice ; Rabbits ; Cholinesterase inhibitors ; In vivo analysis ; Substrates ; Blood chemical analysis ; Carbaryl ; Reprints ; Acetic acid/butyl-dimethyl ; Toxic substances ; Parathion|
Blood cholinesterase activity was measured in the monkey, dog, rat, mouse, and rabbit. The use of the substrate, dimethyl butyl acetate, resulted in expected values for the monkey, dog, and rabbit, but the cholinesterase activity of the rat and mouse was quite elevated. In vivo cholinesterase inhibition resulted in lower values in all animals. Dimethyl butyl acetate was indicated an acceptable substrate for measuring cholinesterase activity except in the mouse and rat, where high levels of non-specific esterases complicated interpretation.
contained in PB-280 889 titled Journal Articles on Toxicology. Group 14.