Record Display for the EPA National Library Catalog

RECORD NUMBER: 45 OF 64

OLS Field Name OLS Field Data
Main Title Measurement of Blood Cholinesterase Activity in Laboratory Animals Utilizing Dimethylbutyl Acetate as a Substrate.
Author Cranmer, Morris F. ; Peoples., Anita J. ;
CORP Author Environmental Protection Agency, Perrine, Fla. Perrine Primate Lab.
Year Published 1973
Report Number found in PB-280 889
Stock Number PB-280 902, found in PB-280 889
Additional Subjects Cholinesterase ; Pesticides ; Toxicology ; Enzymes ; Acetic acid ; Activity ; Laboratory animals ; Experimental data ; Monkeys ; Dogs ; Rats ; Mice ; Rabbits ; Cholinesterase inhibitors ; In vivo analysis ; Substrates ; Blood chemical analysis ; Carbaryl ; Reprints ; Acetic acid/butyl-dimethyl ; Toxic substances ; Parathion
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB-280 902 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 4p
Abstract
Blood cholinesterase activity was measured in the monkey, dog, rat, mouse, and rabbit. The use of the substrate, dimethyl butyl acetate, resulted in expected values for the monkey, dog, and rabbit, but the cholinesterase activity of the rat and mouse was quite elevated. In vivo cholinesterase inhibition resulted in lower values in all animals. Dimethyl butyl acetate was indicated an acceptable substrate for measuring cholinesterase activity except in the mouse and rat, where high levels of non-specific esterases complicated interpretation.
Notes
contained in PB-280 889 titled Journal Articles on Toxicology. Group 14.