Record Display for the EPA National Library Catalog

RECORD NUMBER: 8 OF 39

OLS Field Name OLS Field Data
Main Title Biochemical, Functional and Morphological Indicators of Neurotoxicity: Effects of Acute Administration of Trimethyltin to the Developing Rat.
Author Miller, D. B. ; O'Callaghan, J. P. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1984
Report Number EPA/600/J-84/262;
Stock Number PB85-193845
Additional Subjects Organometallic compounds ; Toxicity ; Morphology ; Bioassay ; Rats ; Brain ; Hippocampus ; Behavior ; Learning ; Trimethyltin compounds ; Neutrotoxins ; Dose rate
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB85-193845 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/21/1988
Collation 10p
Abstract
The neurotoxic organometal, trimethyltin (TMT), was administered to rats on postnatal day (PND)5. Neurotoxicity was assessed throughout subsequent development using morphological, biochemical and functional endpoints. These consisted of brain weight measures and histology (morphology), assays of nervous system-specific proteins (biochemistry) and neurobehavioral indices of activity and learning (function). All three indices were affected.