Record Display for the EPA National Library Catalog

RECORD NUMBER: 14 OF 117

OLS Field Name OLS Field Data
Main Title Correlation of Effects of Inhaled Versus Intratracheally Injected Metals on Susceptibility to Respiratory Infection in Mice.
Author Hatch, Gary E. ; Slade, Ralph ; Boykin, Elizabeth ; Hu, Ping C. ; Miller, Frederick J. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1981
Stock Number PB83-149302
Additional Subjects Metals ; Toxicology ; Respiratory diseases ; Bacteria ; Mice ; Laboratory animals ; Tolerances(Physiology) ; Respiration ; Mortality ; Reprints ; Air pollution effects(Animals)
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB83-149302 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 9p
Abstract
Effects of intratracheally administered air pollutant chemicals on susceptibility of mice to infection by aerosolized bacteria were compared with effects of the same chemicals previously studied by the inhalation route. Out of 22 compounds previously studied by inhalation, the same 3 that caused significantly increased mortality because of infection after a 3-h exposure to 1 to 2 mg/cu. m. showed large mortality increases when administered by intratracheal injection at lung concentrations calculated to be equivalent to those achieved during inhalation exposures.