Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Evaluation of Tests with Early Life Stages of Fish for Predicting Long-Term Toxicity.
Author McKim., James M. ;
CORP Author Environmental Research Lab.-Duluth, Minn.
Year Published 1977
Report Number EPA/600/J-77/046;
Stock Number PB-272 769
Additional Subjects Pesticides ; Toxicity ; Fishes ; Water pollution ; Life cycles ; Metals ; Sewage ; Biphenyl ; Chlorine organic compounds ; Survival ; Evaluation ; Growth ; Concentration(Composition) ; Time ; Exposure ; Sensitivity ; Predictions ; Reprints ; Biphenyl/chloro ; Polychlorinated biphenyls
Library Call Number Additional Info Location Last
NTIS  PB-272 769 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 10p
Partial and complete life-cycle toxicity tests with fish, involving all developmental stages, have been used extensively in the establishment of water-quality criteria for aquatic life. During extended chronic exposures of fish to selected toxicants, certain developmental stages have frequently shown a greater sensitivity than others. In 56 life-cycle toxicity tests completed during the last decade with 34 organic and inorganic chemicals and four species of fish, the embryo-larval and early juvenile life stages were the most, or among the most, sensitive. Tests with these stages can be used to estimate the maximum acceptable toxicant concentration (MATC) within a factor of two in most cases. Therefore, toxicity tests with these early life stages of fish should be useful in establishing water-quality criteria and in screening large numbers of chemicals.