Record Display for the EPA National Library Catalog

RECORD NUMBER: 28 OF 47

OLS Field Name OLS Field Data
Main Title Effects of Carinal Ridge Shapes on Lung Airstreams.
Author Martonen, T. B. ; Yang, Y. ; Xue, Z. Q. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;North Carolina Univ. at Chapel Hill. ;North Carolina State Univ. at Raleigh. Dept. of Mathematics.
Publisher c1994
Year Published 1994
Report Number EPA/600/J-94/406;
Stock Number PB95-125407
Additional Subjects Lung ; Anatomy ; Air pollution ; Aerosols ; Risk assessment ; Trachea ; Bronchi ; Inspiratory capacity ; Fluid dynamics ; Reprints ; Carinal ridge ; Airstreams
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB95-125407 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 03/06/1995
Collation 22p
Abstract
Experimental tests cited herein have established that the deposits of inhaled particles may be highly concentrated at carinal ridges within lung bifurcations. The deposition patterns, therefore, have immediate implications to risk assessment programs and aerosol therapy protocols. Herein, the software FIDAP was employed to study the effects of carinal ridge shapes upon fluid dynamics patterns. A series of well-defined geometric shapes (symmetric and asymmetric) were examined. For each case, a wide range of physiologically realistic flows were considered which corresponded to respiratory intensities for sedentary, light, and heavy activities. The results varied in a systematic manner. By relating fluid dynamics patterns to particle behaviors, the results have inhalation toxicology and aerosol therapy relevance because, for example, bronchogenic carcinomas are selectively distributed within the tracheobronchial tree and certain receptors are known to be preferentially located at airway dividing sites.