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RECORD NUMBER: 3 OF 3

OLS Field Name OLS Field Data
Main Title Effects of atmospheric pollutants on human physiologic function [microform] /
Author Hackney, Jack D.
Other Authors
Author Title of a Work
Malindzak, George S.
CORP Author Professional Staff Association of the Rancho Los Amigos Hospital, Inc., Downey, Calif.;Health Effects Research Lab., Research Triangle Park, N.C.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Health Effects Research Labaratory,
Year Published 1977
Report Number EPA/600/1-77/007; EPA-R-801396
Stock Number PB-265 846
Subjects Air Pollutants--physiology.
Additional Subjects Smog ; Ozone ; Physiological effects ; Public health ; Carbon monoxide ; Air pollution ; Humans ; Environment simulation ; Experimental data ; Sulfur dioxide ; Nitrogen dioxide ; Respiratory system ; Erythrocytes ; Blood ; Biochemistry ; Concentration(Composition) ; California ; Canada ; Respiratory diseases ; Air pollution effects(Humans) ; Photochemical oxidants ; Environmental health
Internet Access
Description Access URL
http://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=2000Y9JD.PDF
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB-265 846 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation iv, 108 p.
Abstract
Short-term health effects of common ambient air pollutants, particularly photochemical oxidants, were investigated under controlled conditions simulating typical ambient exposures. Volunteer subjects were exposed, in an environmental control chamber providing highly purified background air, to single pollutants or mixtures under conditions of realistic secondary stress (heat and intermittent exercise). Normal men exposed to ozone (O3) showed respiratory symptoms, pulmonary function decrement, and alterations in red-cell biochemistry. These effects were dose-related, with apparent 'threshold' for detectable effect levels as low as 0.2-0.3 ppm in a 2-hr exposure for the most sensitive subjects. Addition of 0.3 ppm nitrogen dioxide (NO2) and 30 ppm carbon monoxide (CO) did not noticeably enhance adverse effects of O3, but addition of 0.37 ppm sulfur dioxide (SO2) to 0.37 ppm O3 produced slightly greater effects than did 0.37 ppm O3 alone. Subjects with asthma of clinical airway hyperactivity appeared to experience more severe effects of O3 than normals, and subjects chronically exposed to ambient O3 appeared to be less reactive than those living in non-O3-polluted areas.
Notes
"EPA-600/1-77-007." "January 1977." Microform.