Main Title |
Effect of Ozone Exposure upon Hepatic and Serum Ascorbic Acid Levels in Male Sprague-Dawley Rats. |
Author |
Calabrese, E. J. ;
Moore, G. S. ;
Weeks, B. L. ;
Stoddard, A. ;
|
CORP Author |
Massachusetts Univ., Amherst. Dept. of Public Health.;Health Effects Research Lab., Research Triangle Park, NC. |
Year Published |
1983 |
Report Number |
EPA-R-805797; EPA/600/J-83/275; |
Stock Number |
PB85-173219 |
Additional Subjects |
Ozone ;
Ascorbic acid ;
Toxicology ;
Exposure ;
Bioassay ;
Rats ;
Mice ;
Laboratory animals ;
Reprints ;
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB85-173219 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
18p |
Abstract |
Exposure of male Sprague-Dawley rats to 0.3 ppm ozone for 3 hours resulted in a time-delayed increase in serum and hepatic reduced ascorbic acid levels as compared to controls (0.0 ppm O3) which exhibited an immediate increase in hepatic and serum ascorbic levels. After 24 hours ascorbic acid levels in both groups approached but did not return to pre-exposure values. The immediate increase in ascorbic acid levels in the controls was unexpected and may reflect previously unrecognized chamber and/or handling effects. (Copyright (c) 1983 by Marcel Dekker, Inc.) |