Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Mathematical Modeling of Ozone Absorption in the Lower Respiratory Tract.
Author Overton, J. ; Graham, R. C. ; Miller, F. J. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. ;Northrop Services, Inc., Research Triangle Park, NC.
Year Published 1987
Report Number EPA/600/D-88/141;
Stock Number PB88-225073
Additional Subjects Toxicology ; Ozone ; Adsorption ; Respiratory systems ; Mathematical models ; Air pollution ; Chemical reactions ; Inhalation ; Dosimetry models
Library Call Number Additional Info Location Last
NTIS  PB88-225073 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 12/29/1988
Collation 13p
A mathematical O3 dosimetry model has been developed for simulating the local absorption of O3 in the lower respiratory tract (LRT) of animals and man. The model takes into account LRT anatomy, transport in the lumen and air spaces, transport and chemical reactions in the liquid layers and in the underlying tissue and capillaries. Differential equations are used to describe the processes of transport and chemical reactions; solutions are obtained numerically. Simulations are illustrated with results of two investigations: the effect of anatomical models on predicted LRT uptake of O3 in rat and guinea pig, and the effect of exercise on the uptake and distribution of ozone in the LRT of man.