Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Research Issues Identified Through the Use of Mathematical Dosimetry Models: Ozone.
Author Miller, F. J. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1988
Report Number EPA/600/D-88/038;
Stock Number PB88-171186
Additional Subjects Ozone ; Exposure ; Mathematical models ; Toxicity ; Hazardous materials ; Pollution ; Respiratory diseases ; Lung ; Dosimetry ; Toxic substances
Library Call Number Additional Info Location Last
NTIS  PB88-171186 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 06/21/1988
Collation 22p
Knowledge of dose is a fundamental starting point in the evaluation of the toxicity of chemicals, not only for interspecies comparisons but also for designing experiments that elucidate mechanisms of action and that identify issues or research areas for further study. Using a mathematical dosimetry model for ozone, the paper mainly focuses on how models can be used to identify dosimetric research issues and lead to implementation of research projects that address them. Critical to these efforts are sensitivity analyses wherein model parameters are varied and effects on predicted dose are quantified. The use of models to identify research projects and issues reflects an application which may in the long-term be equally important as the more traditionally recognized function of predicting the dose of a chemical at target sites.