Main Title |
Possible approaches to the health effects testing of fuels and fuel additives / |
Author |
Gause, Emily M. ;
Meltz, Martin L. ;
Greene, Nathan D.
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Other Authors |
|
CORP Author |
Southwest Foundation for Research and Education, San Antonio, TX.;Health Effects Research Lab., Research Triangle Park, NC. |
Publisher |
Environmental Monitoring and Support Laboratory, U.S. Environmental Protection Agency, |
Year Published |
1981 |
Report Number |
EPA-68-02-2286; EPA-600/2-81-235; EPA-600-R-81-114 |
Stock Number |
PB82-132002 |
OCLC Number |
70515843 |
Subjects |
Fuel ;
Fuel--Toxicology
|
Additional Subjects |
Fuel additives ;
Fuels ;
Toxicology ;
Reproduction(Biology) ;
Tests ;
Bioassay ;
Combustion products ;
Air pollution ;
Data collection ;
Hazards ;
Exposure ;
Physical properties ;
Chemical properties ;
Mutagenesis ;
Carcinogenesis ;
Teratogenesis ;
Air pollution effects(Humans)
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Internet Access |
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Local Library Info |
Library |
Local Subject |
Local Note |
ELC |
|
4/16/2012 - This is at NSCEP under EPA-600-R-81-114. At ELC it was shelved and sent to digitization under EPA 600-2-81-235. Correct call number when unpacked from digization at ELC. Kirk Nims. |
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Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
ELCD |
EPA 600-2-81-235 |
|
NVFEL Library/Ann Arbor, MI |
10/26/2011 |
NTIS |
PB82-132002 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
viii, 115, [50] leaves ; 30 cm. |
Abstract |
This document describes possible approaches to the testing of fuels and fuel additives for potential health effects. Such health effects testing is required of the manufacturer of a fuel or fuel additive. The health effects tests must include but are not limited to carcinogenic, teratogenic, or mutagenic effects. In order to determine the appropriate protocol for health effects testing, the following areas are discussed: (1) test materials, (2) relationship of physical and chemical properties of test materials to physiological distribution and biological activity, (3) weighing factors involved in determining an approach to appropriate health effects testing, (4) route and mode of exposure. The possible health effects tests described are organized into the following areas: (1) toxicity (with an emphasis on pulmonary effects), (2) mutagenesis, (3) carcinogenesis, (4) teratogenesis and reproductive performance. The final chapter describes two possible approaches to testing. This report is a technical background document and is not intended to serve as a health effects testing protocol for fuels and fuel additives. |
Notes |
"PB82-132002." "EPA-600/2-81-235." Reproduced by: National Technical Information Services, U.S. Department of Commerce, Springfield, VA. Includes bibliographical references. |