Main Title |
Approach for Integration of Toxicological Data (Journal Version). |
Author |
Shirazi, M. A. ;
Lowrie, L. N. ;
|
CORP Author |
Corvallis Environmental Research Lab., OR. ;Northrop Services, Inc./Environmental Sciences, Corvallis, OR. |
Publisher |
c1988 |
Year Published |
1988 |
Report Number |
EPA/600/D-88/253; |
Stock Number |
PB89-129472 |
Additional Subjects |
Responses ;
Toxicology ;
Dosage ;
Sensitivity ;
Tests ;
Bioassay ;
Comparison ;
Reprints ;
Chemicals ;
LC 30
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
NTIS |
PB89-129472 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
19p |
Abstract |
The paper presents an approach for aggregating a group of similar test data into a single mean dose-response curve with error bounds quantifying the variability of the original data. Groups of similar tests are then classified using generalized exponential dose-response functions whose constants define modes of biological response and facilitate calculation of toxicity and sensitivity. Groups of similar data and classes of different groups of tests are used to demonstrate the application and the utility of the approach. (Copyright (c) American Society for Testing and Materials, 1988.) |