Record Display for the EPA National Library Catalog
RECORD NUMBER: 2 OF 5Main Title | Effectiveness of Organophosphorus Complexons in Intratracheal Poisoning with Beryllium Chloride (Effektivnost Fosforoganicheskikh Kompleksonov pri Intratrakhealnom Otravlenii Khloristym Berilliem). | |||||||||||
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Author | Zaugolnikov, S. D. ; Kuznetsov, A. V. ; Matveev, O. G. ; Suntsov., G. D. ; | |||||||||||
CORP Author | Environmental Protection Agency, Research Triangle Park, N.C. Translation Services Section. | |||||||||||
Year Published | 1974 | |||||||||||
Report Number | EPA-TR-27-75; | |||||||||||
Stock Number | PB-237 799-T | |||||||||||
Additional Subjects | Beryllium inorganic compounds ; Pulmonary edema ; Phosphonates ; Toxicology ; Organic phosphorus compounds ; Trachea ; Respiratory system ; Toxic diseases ; Pharmacology ; Laboratory animals ; Experimental data ; Translations ; USSR ; Phosphonic acid/(Calcium-sodium-salt)-(N-N-(diamine-pentamethyd)diethyl)amino | |||||||||||
Holdings |
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Collation | 7p | |||||||||||
Abstract | Experiments conducted on 340 mice and 170 rats gave evidence that the organophosphorus complexon DTPP (calcium-sodium salt of diethylenetriaminepentamethylphosphonic acid), by single intraperitoneal administration, greatly mitigates pulmonary edema, provoked by intratracheal administration of beryllium chloride, and it increases survival of the animals. Radioisotope investigations demonstrated that DTPP contributes to more rapid elimination of the beryllium ion from the body, in cases of intratracheal poisoning with beryllium chloride. |