Record Display for the EPA National Library Catalog

RECORD NUMBER: 39 OF 50

OLS Field Name OLS Field Data
Main Title Toxicity of Hexamethylphosphoramide in Rats.
Author Kimbrough, Renate ; Gaines., Thomas B. ;
CORP Author Communicable Disease Center, Atlanta, Ga.
Year Published 1966
Stock Number PB-280 011
Additional Subjects Pest control ; Toxicology ; Toxicity ; Rats ; Laboratory animals ; Bioassay ; Ingestion(Biology) ; Diet ; Skin(Anatomy) ; Testis ; Reproductive system ; Toxic substances ; Reprints ; Chemosterilants ; Phosphoric triamide/hexamethyl
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB-280 011 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 2p
Abstract
The data show that HMPA has a very specific effect on the testes of rats when fed at a dietary level of 750 p.p.m. which may be compared with a level of 2.500 p.p.m. in food necessary to cause 100 per cent sterility in male flies. This comparison shows that the safety of any future use of HMPA must be based on its moderate toxicity to mammals and on limitation of their contact with it rather than on any important difference in the inherent susceptibility of mammals and insects to the compound.