Record Display for the EPA National Library Catalog
RECORD NUMBER: 22 OF 49Main Title | Identification of Three Previously Unreported Lindane Metabolites from Mammals. | |||||||||||
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Author | Chadwick, Robert W. ; Freal, Joseph J. ; Sovocool, G. Wayne ; Bryden, Charles C. ; Copeland, M. Frank ; | |||||||||||
CORP Author | Health Effects Research Lab., Research Triangle Park, NC. | |||||||||||
Year Published | 1978 | |||||||||||
Report Number | EPA/600/J-78/083; | |||||||||||
Stock Number | PB-290 077 | |||||||||||
Additional Subjects | Insecticides ; Pesticides ; Mammals ; Metabolism ; Chemical analysis ; Identifying ; Urine ; Isolation ; Characteristics ; Liver ; Rats ; Laboratory animals ; Experimental data ; Tables(Data) ; Diets ; Ingestion(Biology) ; Metabolites ; Lindane ; Cyclohexane/hexachloro ; Reprints | |||||||||||
Holdings |
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Collation | 10p | |||||||||||
Abstract | Previously unreported metabolites from the urine of rats treated with lindane have been identified as configurational isomers of 2, 4, 5, 6- and 2, 3, 4, 6-tetrachloro-2-cyclohexen-1-o1. In addition, an intermediate metabolite from the incubation of lindane with liver preparations, under N2, has been identified as the configurational isomer gamma-3, 4, 5, 6-tetrachlorocyclohex-1-ene. The pathways leading to these metabolites appear to have an important role in the metabolism of lindane by mammals. |