Record Display for the EPA National Library Catalog

RECORD NUMBER: 15 OF 17

OLS Field Name OLS Field Data
Main Title Pargyline and gamma-Butyrolactone Enhance Tyrosine Hydroxylase Immunostaining of Nigrostriatal Axons.
Author Haykal-Coates, N. ; O'Callaghan, J. P. ; Reinhard, J. F. ; Jensen, K. F. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC. Neurotoxicology Div. ;ManTech Environmental Technology, Inc., Research Triangle Park, NC. ;Wellcome Research Labs., Research Triangle Park, NC.
Publisher c1991
Year Published 1991
Report Number EPA/600/J-91/211;
Stock Number PB91-243022
Additional Subjects Pargyline ; 4-Butyrolactone ; Tyrosine hydroxylase ; Axons ; Substantia nigra ; Immunohistochemistry ; Pharmacology ; Biosynthesis ; Neuroregulators ; Western blotting ; Reprints ;
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB91-243022 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 11/26/1991
Collation 7p
Abstract
Administration of pargyline or gamma-butyrolactone enhanced immunostaining of tyrosine hydroxylase immunoreactive axons in the striatum. The qualitative characteristics of the enhancement were compound dependent and the enhancement was not associated with an increase in the amount of tyrosine hydroxylase within the striatum. These results demonstrate the pharmacological enhancement of immunostaining for neurotransmitter synthetic enzymes in the absence of increased synthesis. (Copyright (c) 1991 Elsevier Science Publishers B.V.)