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RECORD NUMBER: 234 OF 478

OLS Field Name OLS Field Data
Main Title Influence of Ozone on Pentobarbital-induced Sleeping Time in Mice, Rats, and Hamsters.
Author Graham, Judith A. ; Menzel, Daniel B. ; Miller, Frederick J. ; Illing, Joseph W. ; Gardner, Donald E. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1981
Report Number EPA-600/J-81-247;
Stock Number PB82-249301
Additional Subjects Ozone ; Sleep ; Pentobarbital ; Barbiturates ; Hypnotics and sedatives ; Mice ; Rats ; Hamsters ; Laboratory animals ; Exposure ; Concentration(Composition) ; Reprints ;
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB82-249301 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 12p
Abstract
Prior studies have shown that ozone (O3) increases pentobarbital (PEN)-induced sleeping time (S.T.) in female mice, rats, and hamsters. To investigate some potential mechanisms producing these effects, the authors measured zoxazolamine-induced paralysis time and thiopental- and hexobarbital-induced S.T., all of which were prolonged significantly in mice following a 5-hr exposure to 1960 micrograms O3/cu m (1 ppm).