Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Identification of Three Previously Unreported Lindane Metabolites from Mammals.
Author Chadwick, Robert W. ; Freal, Joseph J. ; Sovocool, G. Wayne ; Bryden, Charles C. ; Copeland, M. Frank ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1978
Report Number EPA/600/J-78/083;
Stock Number PB-290 077
Additional Subjects Insecticides ; Pesticides ; Mammals ; Metabolism ; Chemical analysis ; Identifying ; Urine ; Isolation ; Characteristics ; Liver ; Rats ; Laboratory animals ; Experimental data ; Tables(Data) ; Diets ; Ingestion(Biology) ; Metabolites ; Lindane ; Cyclohexane/hexachloro ; Reprints
Library Call Number Additional Info Location Last
NTIS  PB-290 077 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 10p
Previously unreported metabolites from the urine of rats treated with lindane have been identified as configurational isomers of 2, 4, 5, 6- and 2, 3, 4, 6-tetrachloro-2-cyclohexen-1-o1. In addition, an intermediate metabolite from the incubation of lindane with liver preparations, under N2, has been identified as the configurational isomer gamma-3, 4, 5, 6-tetrachlorocyclohex-1-ene. The pathways leading to these metabolites appear to have an important role in the metabolism of lindane by mammals.