Main Title |
Application of high performance liquid chromatography/mass spectrometry to environmental analysis / |
Author |
Betowski, L. D. ;
Jones, T. L.
|
Other Authors |
|
CORP Author |
Environmental Monitoring Systems Lab., Las Vegas, NV. |
Publisher |
U.S. Environmental Protection Agency, Environmental Monitoring Systems Laboratory, |
Year Published |
1989 |
Report Number |
EPA/600-S4-89-033; EPA/600/4-89/033 |
Stock Number |
PB90-116963 |
OCLC Number |
40828486 |
Subjects |
Pollution--Analysis ;
High performance liquid chromatography ;
Mass spectrometry
|
Additional Subjects |
Mass spectroscopy ;
Chemical analysis ;
Herbicides ;
Azo dyes ;
Chlorine organic compounds ;
Design criteria ;
Performance evaluation ;
Ionization ;
Particle beams ;
Environmental monitoring ;
High performance liquid chromatography ;
Phenyls ;
Dischargers
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
EJBD |
EPA 600-S4-89-033 |
In Binder |
Headquarters Library/Washington,DC |
11/14/2018 |
ELBD ARCHIVE |
EPA 600-S4-89-033 |
In Binder Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
ELBD |
EPA 600-S4-89-033 |
|
AWBERC Library/Cincinnati,OH |
11/21/2023 |
NTIS |
PB90-116963 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
3 pages ; 28 cm |
Abstract |
High performance liquid chromatography (HPLC) coupled with mass spectrometry (MS) is described for the analysis of samples for environmental pollutants. During the course of the work different techniques were used to increase both the sensitivity and specificity of HPLC/MS. These included the utilization of two different interfaces for the mass spectrometer, the thermospray and the particle beam systems. Refinements to the thermospray system were made with the use of a wire-repeller to enhance sensitivity and also to increase the structural information obtained from mass spectra. The operation of the instrument in the discharge negative ionization mode further increased the specificity of these techniques as did the use of a triple quadrupole mass spectrometer in the HPLC/MS system. Two different sets of compounds were used in the study. Organic dyes were used to test the improvements in the system. Since work was performed with dyes previously and since dye compounds encompass a variety of structural functionalities, the dyes made good test compounds. Chlorinated herbicides were studied in an effort to analyze for these compounds directly without having to prepare derivatives before separation. |
Notes |
Jones, T.L. Caption title. At head of title: Project summary. L.D. Betowski, also Project Officer. "December 1989." "EPA/600-S4-89-033." |
Contents Notes |
High performance liquid chromatography (HPLC) coupled with mass spectrometry (MS) is described for the analysis of samples for environmental pollutants. During the course of this work different techniques were used to increase both the sensitivity and specificity of HPLC/MS. These included the utilization of two different interfaces for the mass spectrometer - the thermospray and the particle beam systems. Refinements to the thermospray system were made with the use of a wire-repeller to enhance sensitivity and also to increase the structural information obtained from mass spectra. The operation of the instrument in the discharge negative ionization mode further increased the specificity of these techniques as did the use of a triple quadrupole mass spectrometer in the HPLC/MS system. Two different sets of compounds were used in this study. Organic dyes were used to test the improvements in the system. Since work was performed with dyes previously and since dye compounds encompass a variety of structural functionalities, the dyes made good test compounds. Chlorinated herbicides were studied in an effort to analyze for these compounds directly without having to prepare derivatives before separation. |