Main Title |
Effects of manganese and their modification by hexametaphosphate / |
Author |
Bull, Richard J.
|
CORP Author |
Health Effects Research Lab., Cincinnati, Ohio. Water Quality Div. |
Publisher |
Health Effects Research Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, |
Year Published |
1977 |
Report Number |
EPA/600/1-77/024 |
Stock Number |
PB-272 264 |
OCLC Number |
14697614 |
Subjects |
Manganese ;
Trace elements in animal nutrition ;
Trace elements in annimal nutrition
|
Additional Subjects |
Manganese ;
Toxicity ;
Dopamine ;
Ingestion(Biology) ;
Dosage ;
Rats ;
Laboratory animals ;
Experimental data ;
Potable water ;
Water supply ;
Recommendations ;
Toxicology ;
Water treatment ;
Physiological effects ;
Exposure ;
Nervous system disorders ;
Tables(Data) ;
Standards ;
Inorganic phosphates ;
Environmental health ;
Water pollution effects(Humans) ;
Maximum permissible exposure level ;
Threshold limit values ;
Occupational safety and health ;
Toxic tolerances ;
Metaphosphoric acid
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
EJBD |
EPA 600-1-77-024 |
c.1 |
Headquarters Library/Washington,DC |
04/14/2014 |
EKCD |
EPA-600/1-77-024 |
|
CEMM/GEMMD Library/Gulf Breeze,FL |
05/29/2018 |
ELBD ARCHIVE |
EPA-600-1-77-024 |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
ELBD |
EPA 600-1-77-024 |
|
AWBERC Library/Cincinnati,OH |
09/02/2016 |
NTIS |
PB-272 264 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
20 pages ; 28 cm |
Abstract |
The ability of oral Mn(+2) to produce the depletions of dopamine in the corpus striata characteristic of the Parkinson-like syndrome in manganese workers was examined in rats. A second objective of this work was to study the biological interactions between Mn(+2) and sodium hexametaphosphate ((NaPO3)6) administered simultaneously in drinking water. The authors conclude that Mn(+2) in drinking water presents little hazard in terms of central nervous system involvement in a homogeneous population. The involvement of genetic factors which have been suggested to account for the sporadic occurrence of Parkinson-like symptoms in Mn(+2) workers can not be excluded. The use of (NaPO3)6 for Mn(+2) complexation as an alternative to removal in drinking water treatment appears safe from a health standpoint if carefully controlled to avoid excessive amounts of (NaPO3)6. |
Notes |
"May 1977." |