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RECORD NUMBER: 4 OF 4

OLS Field Name OLS Field Data
Main Title Synthesis and Reactions of a Proposed DDT Metabolite, 2,2-bis(p-Chlorophenyl)acetaldehyde.
Author McKinney, J. D. ; Boozer, E. L. ; Hopkins, H. P. ; Suggs., J. E. ;
CORP Author Food and Drug Administration, Atlanta, Ga. Atlanta Toxicology Branch.
Year Published 1969
Stock Number PB-274 740
Additional Subjects Pesticides ; Synthesis(Chemistry) ; Chlorine organic compounds ; Metabolism ; Chemical reactions ; Reprints ; Acetaldehyde/dichloro-diphenyl
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB-274 740 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 2p
Abstract
Studies of the metabolism of DDT led to the preparation of 2,2-bis(p-chlorophenyl)acetaldehyde (I) in order to investigate the possibility of its intermediacy in DDT metabolism. Results of attempts to reproduce a reported synthesis of I have shown that both this report and an even earlier report of a different synthetic approach are incorrect. It was observed in this laboratory that I undergoes oxidative deformylation under mild oxidizing conditions to form the benzophenone (II). In comparison, the o,o'-isomer was quite stable under the same conditions. These results are of theoretical interest and may have biological significance.