Main Title |
Investigation of cancer risk assessment methods summary / |
Author |
Allen, B. C. ;
Shipp, A. M. ;
Crump, K. S. ;
Kilian, B. ;
Hogg, M. L.
|
Other Authors |
|
CORP Author |
Clement Associates, Inc., Ruston, LA.;Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.;Department of Defense, Washington, DC.;Electric Power Research Inst., Palo Alto, CA.;Risk Science Inst., Washington, DC. |
Publisher |
U.S. Dept. of Commerce, National Technical Information Service, |
Year Published |
1987 |
Report Number |
EPA/600/6-87/007A; EPA-68-01-6807 |
Stock Number |
PB88-127105 |
OCLC Number |
21819524 |
Subjects |
Carcinogenicity testing ;
Carcinogens--Identification ;
Chemicals--Physiological effect
|
Additional Subjects |
Magnetic neoplasms ;
Methodology ;
Cancer ;
Risk assessments ;
Carcinogenesis ;
Toxic substances ;
Health risks
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
ELBD |
EPA 600-6-87-007a |
|
AWBERC Library/Cincinnati,OH |
01/12/2009 |
NTIS |
PB88-127105 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
v, 61 p. : ill. ; 28 cm. |
Abstract |
The major focus of the study is upon making quantitative comparisons of carcinogenic potency in animals and humans for 23 chemicals for which suitable animal and human data exists. These comparisons are based upon estimates of risk related doses (RRDs) obtained from both animal and human data. An RRD represents the average daily dose per body weight of a chemical that would result in an extra cancer risk of 25%. Animal data on these and 21 other chemicals of interest to the EPA and the DOD are coded into an animal data base that permits evaluation by computer of many risk assessment approaches. The report is the result of a two-year study to examine the assumptions, other than those involving low dose extrapolation, used in quantitative cancer risk assessment. The study was funded by the Department of Defense (through an interagency transfer of funds to the Environmental Protection Agency (EPA)), the EPA, the Electric Power Research Institute and, in its latter stages, by the Risk Science Institute. |
Notes |
"EPA/600/6-87/007a." |