Record Display for the EPA National Library Catalog

RECORD NUMBER: 7 OF 9

OLS Field Name OLS Field Data
Main Title Risk Assessment Is a Developing Science: Approaches to Improve Evaluation of Single Chemicals and Chemical Mixtures.
Author Stara, J. F. ; Bruins, R. J. F. ; Dourson, M. L. ; Erdreich, L. S. ; Hertzberg, R. C. ;
CORP Author Environmental Protection Agency, Cincinnati, OH. Environmental Criteria and Assessment Office.
Publisher 1989
Year Published 1989
Report Number EPA/600/D-89/033;
Stock Number PB89-223952
Additional Subjects Environmental pollution ; Public health ; Hazardous materials ; Carcinogens ; Exposure ; Measurement ; Reprints ; Risk assessment ; Dose response relationships ; Health effects
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB89-223952 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 12/18/1989
Collation 28p
Abstract
The US Environmental Protection Agency is engaged in the development of risk assessment guidelines and methodologies as part of the regulatory program of the Agency. The primary goal of the Agency was originally to accurately assess the effects of human exposure to single chemicals in a single medium (e.g. water) over a human lifetime. Assessment methods for estimating low-dose lifetime cancer risk for known or suspected human carcinogens, or long-term acceptable daily intake (ADI) levels for threshold-acting toxicants, were developed and successfully applied to meet this need. Now there is an increasing need for methods which address more complex exposure situations, including multichemical, multiroute, and partial-lifetime exposures. Improvements in the current methods are also needed. Several issues now under study are briefly described.