Record Display for the EPA National Library Catalog

RECORD NUMBER: 7 OF 12

OLS Field Name OLS Field Data
Main Title Effects of Chronic Manganese (Mn3O4) Exposure on Selected Reproductive Parameters in Rats.
Author Laskey, J. W. ; Rehnberg, G. L. ; Hein, J. F. ; Carter, S. D. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1982
Report Number EPA-600/J-81-328;
Stock Number PB84-174366
Additional Subjects Managanese ; Toxicology ; Exposure ; Rats ; Laboratory animals ; Reproduction(Biology) ; Diets ; Reprints ;
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB84-174366 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 13p
Abstract
Long-Evans rats were chronically exposed to dietary manganese beginning on d 1 of gestation and continuing through 224 d of age. Dietary concentrations of manganese were 350, 1050, and 3500 ppm and were applied in either normal Fe 240 (ppm) or a low-Fe (20 ppm) basal diet. General toxic effects were apparent in young animals at a dietary dose of 3500 ppm Mn and were enhanced by concomitant Fe deficiency. Fertility was reduced in the group exposed to 3500 ppm Mn with a diet containing sufficient Fe. Male reproductive development was delayed by Mn treatment, as measured by testes weight, sperm count, and serum follicle-stimulating hormone and testosterone concentrations.