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RECORD NUMBER: 21 OF 25

OLS Field Name OLS Field Data
Main Title Sodium Chlorite Administration in Long-Evans Rats: Reproductive and Endocrine Effects.
Author Carlton, B. D. ; Habash, D. L. ; Basaran, A. H. ; George, E. L. ; Smith, M. K. ;
CORP Author Health Effects Research Lab., Cincinnati, OH. ;Battelle Columbus Div., OH.
Year Published 1987
Report Number EPA/600/J-87/023;
Stock Number PB87-196176
Additional Subjects Sodium chlorites ; Exposure ; Water pollution ; Public health ; Rats ; Toxicity ; Reproduction(Biology) ; Endocrinology ; Reprints ;
Holdings
Library Call Number Additional Info Location Last
Modified
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Status
NTIS  PB87-196176 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/21/1988
Collation 11p
Abstract
Long-Evans rats, 4-6 weeks of age, were given access to 0, 1, 10, or 100 ppm sodium chlorite in deionized water ad libitum as drinking water. Males were evaluated for sperm parameters and reproductive tract histopathology following the breeding. Females were exposed throughout gestation and lactation. Dams and pups were necropsied at weaning. Groups of males were exposed to 0, 10, 100, or 500 ppm ad libitum in the drinking water to confirm observed subtle reproductive effects and examine dose-effect relationships. Increases in the percent abnormal sperm morphology and decreases in sperm direct progressive movement were observed for adult males at chlorite levels of 100 ppm or 500 ppm. (Copyright (c) 1987 by Academic Press, Inc.)