Main Title |
Health assessment document for manganese. |
Author |
Bilinski, H. ;
Bruins, R. J. F. ;
Erdreich, L. ;
Fugas, M. ;
Kello, D. ;
Erdreich, Linda S.
|
CORP Author |
United States. Environmental Protection Agency. Environmental Criteria and Assessment Office.; Environmental Protection Agency, Cincinnati, OH. Environmental Criteria and Assessment Office. |
Publisher |
U.S. Environmental Protection Agency, Office of Research and Development, Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, |
Year Published |
1984 |
Report Number |
EPA-600/8-83-013F |
Stock Number |
PB84-229954 |
OCLC Number |
12940364 |
Subjects |
Manganese--Toxicology
|
Additional Subjects |
Manganese--Toxicology ;
Air pollution ;
Manganese ;
Evaluation ;
Exposure ;
Public health ;
Toxicity ;
Epidemiology ;
Health hazards ;
Environmental transport ;
Air pollution effects(Humans) ;
Environment protection ;
Environmental persistence ;
Carcinogenesis ;
Mutagens ;
Teratogens
|
Internet Access |
|
Holdings |
Library |
Call Number |
Additional Info |
Location |
Last Modified |
Checkout Status |
EHAM |
RA1231.M4EPA-600 8-83-013F |
|
Region 1 Library/Boston,MA |
04/29/2016 |
EJED |
EPA 600/8-83-013F |
|
OCSPP Chemical Library/Washington,DC |
01/01/1988 |
EKBD |
EPA-600/8-83-013F |
|
Research Triangle Park Library/RTP, NC |
08/02/1996 |
ELBD ARCHIVE |
EPA 600-8-83-013F |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
DISPERSAL |
ERAD |
EPA 600/8-83-013F |
|
Region 9 Library/San Francisco,CA |
02/26/2013 |
ESAD |
EPA 600-8-83-013F |
|
Region 10 Library/Seattle,WA |
07/29/2005 |
NTIS |
PB84-229954 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
Collation |
1 volume (various pagings) : illustrations ; 28 cm |
Abstract |
The document evaluates data on occurrence, sources, and transport of manganese in the environment and data on metabolism, pharmacokinetics, laboratory toxicological and epidemiologic studies to determine the nature and dose response relationship of potential health effects on humans. Nationwide air sampling data indicate that mean manganese concentrations have declined from 0.11 micrograms per cu. m. in 1953-1957 to 0.033 micrograms per cu. m. in 1982. The effects of major concern to humans exposed to manganese are on neurological and on pulmonary function. The CNS effects have been observed in humans at exposure levels above 5 mg/cu. m. and are incapacitating and generally irreversible. Data are equivocal between 1 and 5 mg/cu. m. but suggest decreased prevalence. There are no reports of these effects below 0.3 mg/cu. m. exposure. Pneumonia and chronic bronchitis occur at levels which are associated with neurological effects. Reduced lung function has been reported in children exposed to an estimated 3-11 micrograms per cu. m. from emission of a ferromanganese plant. However, studies of workers exposed to 40 micrograms per cu. m. did not show respiratory symptoms. Animal studies qualitatively support pulmonary effects of manganese exposure. Respiratory symptoms occur at lower levels than neurological symptoms and are therefore considered to be the critical effect based on available data. |
Notes |
"August 1984"--Cover. "EPA-600/8-83-013F." "Final report." Includes bibliographical references. "May 1984." |