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OLS Field Name OLS Field Data
Main Title Characterizing the genotoxicity of hazardous industrial wastes and effluents using short-term bioassays /
Author Houck, Virginia Stewart. ; DeMarini, D. M.
Other Authors
Author Title of a Work
DeMarini, David M.
Health Effects Research Laboratory.
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Health Effects Research Laboratory,
Year Published 1989
Report Number EPA/600/D-89/153
Stock Number PB90-116732
Additional Subjects Industrial wastes ; Effluents ; Toxicity ; Salmonella typhimurium ; Distillation ; Exposure ; Paper industry ; Textile industry ; Chemical industry ; Decontamination ; Mutagenicity tests ; Toxic substances ; DNA damage
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB90-116732 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 01/01/1988
Collation 61 pages : illustrations ; 28 cm
Abstract
The paper demonstrates that short-term bioassays can reliably and expeditiously measure the genotoxic potential of hazardous industrial wastes and effluents. Petrochemical wastes have been studied in detail, especially discharges from chemical manufacturing plants and textile and dye effluents. However, there is little information on effluents from pesticide manufacturers. The most extensive evaluations have been conducted on effluents from pulp and paper mills. These studies have shown which pulping plants generate the most genotoxic effluents, which process wastes are most hazardous, have isolated and identified the compounds responsible for the genotoxic activity, have described the environmental fate of these compounds, have evaluated the types of genetic damage likely to occur upon exposure to the effluents, and have identified several treatment methods that effectively reduce the genotoxicity of the effluents. The coupling of bioassays for biological analysis with chemical evaluation provides the most powerful approach to assessing the overall health effects of complex industrial wastes and effluents.
Notes
"EPA/600/D-89/153." Includes bibliographical references. Microfiche.