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RECORD NUMBER: 7 OF 15

OLS Field Name OLS Field Data
Main Title Effect of Chronic Exposure to EPN and to Guthion on the Critical Swimming Speed and Brain Acetylcholinesterase Activity of 'Cyprinodon variegatus'.
Author Cripe, G. M. ; Goodman, L. R. ; Hansen, D. J. ;
CORP Author Environmental Research Lab., Gulf Breeze, FL.
Year Published 1984
Report Number EPA/600/J-84/190;
Stock Number PB85-160158
Additional Subjects Pesticides ; Minnows ; Toxicity ; Water pollution ; Survival ; Tests ; Pesticides ; Phosphorus organic compounds ; Swimming ; Acetylcholinesterase ; Life cycles ; Growth ; Reproduction(Biology) ; Bioassay ; Reprints ; Cyprinodon variegatus ; Sheepshead minnows ; EPN insecticide ; Guthion ; Phosphonothioic acid/(ethyl-ester)-(nitrophenyl-ester)-phenyl ; Phosphosphorodiathioic acid/(dimethyl)-(oxobenzotriaziryl)methyl
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NTIS  PB85-160158 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/21/1988
Collation 13p
Abstract
Swimming performance of the Sheepshead minnow, Cyprinodon variegatus, was measured in a stamina tunnel at the end of life-cycle toxicity tests with the organophosphate pesticides, EPN and Guthion. Swimming stamina was affected by 2.2 micrograms EPN/l but not by 0.88 micrograms EPN/l; these concentrations are about one half of those that significantly affect survival, growth or reproduction. Fish brain acetylcholinesterase (AChE) activity, assayed by the pH-Stat method, was inhibited 72% by 0.88 micrograms EPN/l and 83% by 2.2 micrograms EPN/l. Swimming performance was not affected by Guthion concentrations up to 0.5 micrograms/l; this concentration reduced survival and inhibited AChE 78%.