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RECORD NUMBER: 6 OF 11

OLS Field Name OLS Field Data
Main Title Ocular Chondrosarcomas in 'Rivulus marmoratus' Poey (Short Communication).
Author Courtney, L. A. ; Fournie, J. W. ;
CORP Author Environmental Research Lab., Gulf Breeze, FL.
Publisher c1991
Year Published 1991
Report Number EPA/600/J-91/101 ;CONTRIB-679;
Stock Number PB91-206946
Additional Subjects Fish diseases ; Chondrosarcoma ; Eye neoplasms ; Marine biology ; Cell differentiation ; Histology ; Pathology ; Reprints ; Rivulus marmoratus
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NTIS  PB91-206946 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 11/26/1991
Collation 8p
Abstract
Only one documented case of a malignant cartilaginous tumor has been previously reported from fish, a large cranial chondrosarcoma from the paddlefish, Polyodon spathula (Walbaum). Described here are two chondrosarcomas diagnosed from adult laboratory-reared Rivulus marmoratus Poey, the first reports of the tumor type from an atheriniform fish. Histologically, the tumors consisted of cartilage in various stages of differentiation. These ranged from poorly differentiated areas consisting of a highly cellular, primitive mesenchymal component with numerous mitotic figures and extensive anaplasia to well-differentiated portions expressed as scattered foci of mature cartilage consisting of single and multiple chondrocytes isolated within lacunae. The lesions, possibly arising from the sclera, were invasive into the eye, with elements of the choroid and striated muscle trapped within the tumor matrix.