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RECORD NUMBER: 32 OF 35

OLS Field Name OLS Field Data
Main Title Utilization of the Rabbit Alveolar Macrophage and Chinese Hamster Ovary Cell for Evaluation of the Toxicity of Particulate Materials. II. Particles from Coal-Related Processes.
Author Garrett, Neil E. ; Campbell, James A. ; Stack, H. Frank ; Waters, Michael D. ; Lewtas, Joellen ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1981
Report Number EPA-600/J-81-097;
Stock Number PB83-209833
Additional Subjects Coal gasification ; Toxicology ; In vitro analysis ; Reprints ; Particulates ; Cytotoxicity
Holdings
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Status
NTIS  PB83-209833 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/23/1988
Collation 14p
Abstract
Rabbit alveolar macrophage (RAM) and Chinese hamster ovary (CHO) cells were used in vitro tests to evaluate the toxicity of particulate effluents from coal gasification, fluidized-bed combustion, and conventional coal combustion. Evaluation of the cytotoxicity of nine samples from coal energy-related processes showed that the sensitivity of the RAM assay was improved substantially when the test was conducted in serum-free media. A linear relationship was observed between percentage cell viability and ATP level in the particle-treated cultures.