Record Display for the EPA National Library Catalog

RECORD NUMBER: 23 OF 29

OLS Field Name OLS Field Data
Main Title Structural properties for determining mechanisms of toxic action /
Author Bradbury, Steven P. ; Lipnick, R. L.
CORP Author Environmental Research Lab.-Duluth, MN.
Publisher U.S. Environmental Protection Agency, Office of Research and Development, Environmental Research Laboratory,
Year Published 1989
Report Number EPA/600/D-89/089
Stock Number PB89-223804
OCLC Number 45013461
Additional Subjects Meetings ; Aquatic ecosystems ; Free radicals ; Pesticides ; Anesthesiology ; Electrophilic reactions ; Phosphorylation ; Fishes ; Toxic substances ; Structure activity relationship
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB89-223804 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation 10 pages ; 28 cm
Abstract
The results of a workshop co-sponsored by EPA through the Health and Environmental Review Division, Office of Toxic Substances and the Environmental Research Laboratory-Duluth, of the Office of Research and Development are briefly summarized as an introduction to a series of manuscripts dealing with the structural properties of chemicals that determine their toxic mechanisms. Results of the workshop are intended to be incorporated in an expert system to predict mechanisms from chemical structure and aid in predictive toxicology applications in the Agency. The goal of the workshop was to review current understanding of fundamental mechanisms, and develop an initial knowledge base on chemical features and properties from which toxic mechanisms could be predicted from structure. Areas addressed included general anesthesia, or narcosis, oxidative phosphorylation uncoupling, electrophile and free-radical reactivity, and a variety of pesticide-based mechanisms.
Notes
EPA/600/D-89/089. PB89-223804. "To be presented to Environmental Health Perspectives." Microfiche.