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RECORD NUMBER: 8 OF 9

OLS Field Name OLS Field Data
Main Title Scientific basis for the development of the international toxicity equivalency factor (I-TEF) method of risk assessment for complex mixtures of dioxins and related compounds /
Author Safe, S. H. ; Kutz, F. W. ; Bottimore, D. P.
Other Authors
Author Title of a Work
Safe, Stephen H.
Kutz, Frederick W.
Bottimore, David P.
CORP Author NATO Committee on the Challenges of Modern Society, Brussels (Belgium). ;Texas A and M Univ., College Station. ;Versar, Inc., Springfield, VA.;Environmental Protection Agency, Washington, DC.
Publisher U.S. Environmental Protection Agency, Office of research and Development ; Committee on the Challenges of Modern Society,
Year Published 1988
Report Number EPA/600/6-90/015; NATO/CCMS 178; EPA-68-02-4245
Stock Number PB91-109991
Subjects Dioxins.
Additional Subjects Dioxins ; Toxicity ; Pollution ; Bioassay ; Risk assessment ; Environmental impacts ; Dosage ; Response ; Rats ; Fly ash ; Pyrolysis ; Municipalities ; Concentration(Composition) ; Exposure ; Humans ; EC50 ; Polychlorinated dibenzo p-dioxins ; Dibenzofurans
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
NTIS  PB91-109991 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 01/01/1988
Collation 63 pages ; 28 cm.
Abstract
The Pilot Study on International Information Exchange on Dioxins and Related Compounds was initiated to apply the cooperative efforts of several nations to address issues assoc. with PCDDs, PCDFs, and related compounds. The three-year study was conducted under the aegis of the CCMS of NATO. The report presents a detailed discussion of the scientific basis for the development of toxicity equivalency factors and provides the toxicity data and methodology used to determine the I-TEFs. Section 2 discusses background information on PCDDs and PCDFs. Section 3 discusses the need for I-TEFs. Section 4 presents the mechanisms of toxicity of these compounds. Section 5 provides a discussion of the development of TEFs from experimental toxicity data.
Notes
Cover title. "Report of the NATO/CCMS Pilot Study on International Information Exchange on Dioxins and Related Compounds"--Page [i]. "December 1988"--Cover. "Contract No. 68-02-4254"--Page [i]. Includes bibliographical references (pages 46-56). Microfiche.