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RECORD NUMBER: 12 OF 37

OLS Field Name OLS Field Data
Main Title EEG (Electroencephalogram) as a Cross Species Indicator of Neurotoxicity.
Author Benignus, V. A. ;
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1984
Report Number EPA/600/J-84/283;
Stock Number PB85-196525
Additional Subjects Electroencephalography ; Reprints ; Neurotoxicology
Holdings
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Status
NTIS  PB85-196525 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. NTIS 06/21/1988
Collation 13p
Abstract
The electroencephalogram (EEG) is a promising measure in the field of neurotoxicology. It can be well quantified by techniques which can be interpreted both physically and statistically. Such quantification schemes are briefly discussed in this paper. However, the quantification of EEG is not trivial in either the mathematical or computational sense. The relationship of EEG to brain function or brain pathology is not very well understood by some standards, perhaps due to poor quantitiative methods or erroneous assumptions about brain-behavior relationships. EEG has a similar appearance across species. Hence the measure has great promise as a cross species indicator of neurotoxicity. Not many quantitatively sound neurotoxicological studies using EEG have been published. It must be strongly emphasized that (a) more methods development is needed before the promise of cross species generality can be realized and (b) naive and/or halfhearted attempts to use this measure are perilous.