Record Display for the EPA National Library Catalog

RECORD NUMBER: 536 OF 4102

Main Title Biomagnification of Bioassay Derived 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Equivalents.
Author Jones, P. D. ; Ankley, G. T. ; Best, D. A. ; Crawford, R. ; DeGalan., N. ;
CORP Author Michigan State Univ., East Lansing. ;National Fisheries Contaminant Research Center, Columbia, MO. ;Ecological Research Services, Inc., Ann Arbor, MI.;Environmental Research Lab.-Duluth, MN.;Fish and Wildlife Service, Washington, DC.
Publisher c1993
Year Published 1993
Report Number EPA/600/J-94/180;
Stock Number PB94-163599
Additional Subjects Pesticides ; Aquatic ecosystems ; Water pollution effects ; Great Lakes ; Reprints ; Bioassay ; Magnification ; Chlorinated hydrocarbons ; Concentration(Composition) ; Herbicides ; Food chains ; Trophic level ; Path of pollutants ; Biochemistry ; Carcinogens ; Dioxin/tetrachloro-p-dibenzo
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NTIS  PB94-163599 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 12p
Abstract
In recent years contamination of the Great Lakes ecosystem with planar chlorinated hydrocarbons (PCHs) has attracted considerable concern due to their known reproductive and teratogenic effects. The H4IIE bioassay has been standardized as a means of measuring the biological potency of a PCH mixture as 2,3,7,8-tetrachloro-p-dibenzodioxin equivalents (TCDD0EQ). Using this bioassay the authors have investigated the biomagnification of TCDD-EQ in a semi-closed ecosystem. The biomagnification of TCDD-EQ is demonstrated and results indicate that the food chain is the major pathway for TCDD-EQ through this ecosystem. The H4IIE assay system is demonstrated to be a viable integrative measure of the total concentration of TCDD-EQ in different trophic levels. (Copyright (c) Pergamon Press Ltd. 1993.)