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Main Title Confounding and selection bias in case control studies /
Author Little, Roderick J. A. ; Rosenbaum, Paul R.
Other Authors
Author Title of a Work
Rosenbaum, Paul R.
CORP Author Office of Radiation Programs, Washington, DC.
Publisher Division of Statistics and Applied Mathematics, Office of Radiation Programs, U.S. Environmental Protection Agency,
Year Published 1981
Report Number EPA 520/8-81-004
Stock Number PB81-194110
OCLC Number 08225428
Subjects Biometry--Mathematical models
Additional Subjects Biometrics ; Epidemiology ; Research ; Design ; Methodology ; Populations ; Statistical analysis
Internet Access
Description Access URL
Library Call Number Additional Info Location Last
ELBD ARCHIVE EPA 520-8-81-004 Received from HQ AWBERC Library/Cincinnati,OH 10/04/2023
NTIS  PB81-194110 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation v, 20 pages ; 28 cm
In case-control studies, the role of adjustments for bias, and in particular the role of matching, has been extensively debated. However, the absence of a formal statement of the problem has led to disagreements, confusion, and occasionally to erroneous conclusions. This paper formulates precisely and answers the following questions. (1) When is it necessary to adjust for a variable Z. (2) Given that the data analysis will adjust for the variable Z, is matching on Z the most efficient method of selecting controls. In answering these questions, the authors draw a sharp distinction between bias caused by confounding in the population and bias caused by the method used to select the sample.
"January 1981." Includes bibliographical references. "EPA 520/8-81-004."