A simple method for estimating enhanced dispersion resulting from the overall effect of buildings is presented and evaluated. A framework for applying the method to general plume dispersion modeling problems is suggested and examples are provided. The Gaussian plume equation has been modified to incorporate building wake enhanced dispersion parameters, and the resulting ground-level plume centerline concentration estimates are compared to 10 sets of field measurements. The results indicate that the method can provide a good correction for the overall effect of adjacent buildings. Better measurements of plume height and the vertical spread of the plume are still needed to resolve some issues. The effect of building influences on plume rise and the determination of plume centerline requires vertical profile measurements. Also, the effect of wind speed should be considered. The cases with the highest wind speed have been observed to behave somewhat extraordinary for several of the studies. Also, the possible effect of vortices should be more fully evaluated. Additional data are needed to fully examine building wake effects. However, in lieu of site-specific information, the methods presented in this report should provide an approximate correction to estimated ground-level centerline concentrations.