Record Display for the EPA National Library Catalog


Main Title Ozone Induced Hematological Changes in Mouse Strains with Differential Levels of Erythrocyte G-6-PD Activity and Vitamin E Status (Journal Version).
Author Calabrese, E. J. ; Moore, G. S. ; Grinberg-Funes, R. ;
CORP Author Massachusetts Univ., Amherst.;Health Effects Research Lab., Research Triangle Park, NC.
Publisher c1985
Year Published 1985
Report Number EPA-R-805797; EPA-600/J-85/537;
Stock Number PB89-110449
Additional Subjects Toxicity ; Ozone ; Tocopherol ; Acetylcholinesterase ; Laboratory animals ; Vitamin deficiencies ; Concentration(Composition) ; Erythrocytes ; Reprints ; Glucosephosphate dehydrogenase
Library Call Number Additional Info Location Last
NTIS  PB89-110449 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 11p
A single short term in vivo exposure (6 hr) to O3 (i.e., 0.3, 0.9, 1.5 ppm) markedly affected several hematological parameters in males of two mouse strains (C57L/J and A/J) reared on either a vitamin E normal or deficient diet. Of particular significance is that at the lowest concentration employed (i.e., 0.3 ppm), O3 induced marked decreases in red cell ACHE and increases in heinz body formation and osmotic fragility in both mouse strains regardless of diet type. Although the two mouse strains markedly differ in the RBC G-6-PD activity, they did not consistently differ in responses to O3 exposure. (Copyright (c) 1985 by Chem-Orbital.)