Viral Entry -- The Many Mechanisms of Viral Membrane Fusion Proteins -- The Role of the Cytoskeleton During Viral Infection -- Nuclear Import in Viral Infections -- Viral RNA Replication in Association with Cellular Membranes -- Synthesis and Quality Control of Viral Membrane Proteins -- Receptor Modulation in Viral replication: HIV, HSV, HHV-8 and HPV: Same Goal, Different Techniques to Interfere with MHC-I Antigen Presentation -- Trafficking of Viral Membrane Proteins. The ability of viruses to exploit cellular functions for their own ends makes them highly effective pathogens and exquisite experimental tools. Work with viruses underpins much of our current understanding of molecular cell biology and related fields. Each of the eight chapters in this volume deals with a specific aspect of viral interactions with cellular membranes. These include chapters on viral entry, viral membrane fusion, viral membrane protein synthesis and transport, viral replication, viral interactions with cytoskeletal systems and the nucleus, the trafficking of viral membrane proteins and viral perturbation of host cell protein trafficking. These chapters should provide both an overview of cellular membrane trafficking mechanisms and viral interactions with these systems, as well as reviews of the current state of each of the fields.