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Main Title Mutagenic and carcinogenic potency of extracts of diesel and related environmental emissions : summary and discussion of the results /
Author Nesnow, Stephen. ; Lewtas, Joellen
Other Authors
Author Title of a Work
Lewtas, Joellen.
CORP Author Health Effects Research Lab., Research Triangle Park, NC.
Publisher U.S. Environmental Protection Agency, Health Effects Research Laboratory,
Year Published 1981
Report Number PB83-149328; EPA-600/J-81-605
Stock Number PB83-149328
OCLC Number 758892849
Subjects Diesel motor exhaust gas--Toxicology--Congresses ; Vehicle Emissions--toxicity--Congresses ; Mutagenicity testing
Additional Subjects Exhaust emissions ; Toxicology ; Bioassay ; Exposure ; Epidemiology ; Reprints ; Mutagenesis ; Carcinogenesis ; Diesel engine exhaust ; Air pollution effects(Humans)
Internet Access
Description Access URL
https://nepis.epa.gov/Exe/ZyPDF.cgi?Dockey=9100XWWY.PDF
Holdings
Library Call Number Additional Info Location Last
Modified
Checkout
Status
ELCD  EPA 600-J-81-605 NVFEL Library/Ann Arbor, MI 10/31/2011
NTIS  PB83-149328 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation pp. 425-429 ; 28 cm.
Abstract
The proposed conversion from gasoline powered automobiles to diesel powered vehicles has prompted the Environmental Protection Agency to evaluate the potential health effects associated with exposure to diesel emissions. At present, there is no direct epidemiological link between this exposure and human health. Therefore, a research program was constructed to compare the health effects associated with diesel emissions with those from other emission sources for which epidemiological information was available. The emission sources chosen were cigarette smoke, roofing tar, and coke oven. An additional comparitive emission source which was evaluated was a gasoline catalyst engine. Respirable particles from a variety of combustion sources have the potential of being carcinogenic and mutagenic. The objective of these studies was to determine the relative biological activity of the organic material adsorbed on these particles in both In Vitro mutagenesis and In Vitro and In Vivo carcinogenesis bioassays.
Notes
"PB83-149328." "EPA-600/J-81-605." Originally published in Environmental International, Vol. 5. Includes bibliographical references (p. 429).
Contents Notes
The proposed conversion from gasoline powered vehicles has prompted the Environmental Protection Agency to evaluate the potential health effects associated with exposure to diesel emissions. At present, there is no direct epidemiological link between this exposure and human health. Therefore, a research program was constructed to compare the health effects associated with diesel emissions with those from other emission sources for which epidemiological information was available. The emission sources chosen were cigarette smoke, roofing tar, and coke oven. An additional comparative emission source which was evaluated was a gasoline catalyst engine. Respirable particles from a variety of combustion sources have the potential of being carcinogenic and mutagenic. The objective of these studies was to determine the relative biological activity of the organic material absorbed on these particles in both In Vitro mutagenesis and In Vitro and In Vivo carcinogenesis bioassays.