| Main Title |
Initial Submission: Teratology Screen in Rats (c-180, C-181, C-182, C-236, C-253, C-254, C-255, C-256, C-257, C-258, C-259) (Final Report) with Attachments and Cover Letter. |
| CORP Author |
Hazleton Labs., Falls Church, VA.; Hoechst Celanese Corp., Summit, NJ.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Year Published |
1991 |
| Report Number |
88-920000178 |
| Stock Number |
OTS0534628 |
| Additional Subjects |
Toxicology ;
Health effects ;
Valeric Acid ;
Reproduction/fertility Effects ;
Teratogenicity ;
Mammals ;
Rats ;
Oral ;
Gavage ;
Toxic substances ;
Laboratory animals ;
CAS No 109-52-4
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS0534628 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
128p |
| Abstract |
Valeric acid (C-180; 109-52-4) was evaluated for developmental effects in 22 female Crl:COBS, CD(SD)BR rats administered 750 mg/kg of the test substance by gavage on days 6 through 15 of gestation. A control group received corn oil. Maternal animals showed an increased incidence of clinical observations (specific signs not reported). Offspring showed an increased incidence of delayed ossification of several bone structures. |
