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Main Title Alpha-Olefin Epoxide C-16 Salmonella/Microsome (Ames) Bacterial Mutagenicity Assay with Cover Letter.
CORP Author Union Carbide Corp., Oak Ridge, TN. Office of Health, Safety, and Environmental Affairs.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Year Published 1984
Report Number 878214505
Stock Number OTS-0206602
Additional Subjects Toxicity ; Mutagenicity assays ; Genotoxicity ; Cells (Biology) ; Gene mutations ; Health effects ; Bacteria ; In vitro ; Concentrations ; Metabolic activation ; Liver cells ; Alkyl epoxides ; Alpha-o1efin epoxide C-16 ; Ames Test ; CAS No 7320-37-8 ; Salmonella typhimurium ; Union Carbide Corporation
Library Call Number Additional Info Location Last
NTIS  OTS-0206602 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 48p
Alpha-o1efin epoxide C-16 was tested for potential mutagenic activity using the Salmonella/microsome bacterial mutagenicity assay (Ames test). alpha-olefin epoxide C-16 was tested in triplicate at five concentrations, ranging from 0.1 allligram to 10 milligrams per plate. The highest concentration was cytotoxic in the mutagenicity test and in a preliminary test to choose appropriate doses. Mutagenic activity was not observed with any of the five bacterial strains tested with or without metabolic activation. alpha-olefin epoxide C-16 was not mutagenic in this screening test.