| Main Title |
Report of the EPA Workshop on the development of risk assessment methodologies for tumor promoters / |
| Author |
Connery, Jan. ;
Spitzer, Hugh L.
|
| Other Authors |
|
| CORP Author |
United States. Environmental Protection Agency. Office of Health and Environmental Assessment. |
| Publisher |
Office of Health and Environmental Assessment and Office of Regulatory Support and Scientific Analysis, Office of Research and Development, U.S. Environmental Protection Agency, |
| Year Published |
1987 |
| Report Number |
EPA/600/9-87/013 |
| Stock Number |
PB88-230743 |
| OCLC Number |
17625877 |
| Subjects |
Cocarcinogens--Research--Congresses ;
Tumors--Genetic aspects--Research--Congresses ;
Genetic engineering--Risk assessment--Congresses
|
| Additional Subjects |
Risk assessment ;
Tumors ;
Methodology ;
Tumor promoters ;
Risk assessment ;
Carcinogenesis
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| EHBD |
EPA/600/9-87/013 |
|
CEMM/ACESD Library/Narragansett,RI |
03/30/2007 |
| EJED |
EPA/600/9-87/013 |
|
OCSPP Chemical Library/Washington,DC |
01/11/2002 |
| EKBD |
EPA-600/9-87-013 |
|
Research Triangle Park Library/RTP, NC |
01/01/1988 |
| ELBD ARCHIVE |
EPA 600/9-87/013 |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
DISPERSAL |
| EMBD |
EPA/600/9-87/013 |
|
NRMRL/GWERD Library/Ada,OK |
08/25/2000 |
| ESAD |
EPA 600-9-87-013 |
|
Region 10 Library/Seattle,WA |
03/23/2010 |
| NTIS |
PB88-230743 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
1 v. (various pagings) : ill. ; 28 cm. |
| Abstract |
At a workshop sponsored by the EPA Office of Research and Development, thirteen expert panelists discussed research needed to support the development of risk assessment methodologies for tumor promoters. The panelists exchanged current data on promotion, identified data gaps, and formulated general and specific research recommendations. Available data suggest that there are probably at least three stages of carcinogenesis - initiation, promotion and progression - and that there are agents that are associated predominantly with these three stages. The panelists agreed that the mechanism of promotion is not currently understood and they suggest that there may be several different mechanisms of promotion. Available data suggest that promotion is substantially different from initiation, and that traditional risk assessment models for carcinogens are not appropriate for promoters. The panelists agreed that not enough data are currently available to assess the risks of promoters, and that substantial research is needed in several areas. |
| Notes |
Distributed to depository libraries in microfiche. "June 1987." Includes bibliographical references (p. 60-66). "EPA/600/9-87/013." |
