Record Display for the EPA National Library Catalog
RECORD NUMBER: 2 OF 2
|OLS Field Name||OLS Field Data|
|Main Title||Tripropylene Glycol Monomethyl Ether (TPGME): 2-week Aerosol Inhalation Toxicity Study in Rats and Mice (Sanitized).|
|CORP Author||Dow Chemical Co., Midland, MI.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.|
|Additional Subjects||Toxicology ; Health effects ; Tripropylene Glycol Monomethyl Ether (25498-49-1) ; Subchronic Toxicity ; Mammals ; Rats ; Inhalation ; Mice ; Toxic substances ; Laboratory animals ; CAS No 25498-49-1|
Groups of 5/sex/species Fischer 344 rats and B6C3F1 mice were exposed to tripropylene glycol monomethyl ether at concentrations of 0, 0.15, 0.36, or 1.01 mg/L for 6 hours/day for a total of 9 days during an 11-day period. An increase in liver weight of both sexes of rats and mice was noted at the two highest dose levels, and in male mice at the low dose. No exposure-related effects were noted on body weights, other organ weights, hematology, clinical chemistry parameters, urinalyses, or gross or histopathology.