||Letter from Union Carbide Chemical and Plastic Company to USEPA containign Preliminary Lab Findings from Immune System Toxicology Study with Attachments.
||Union Carbide Corp., Danbury, CT.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
||12 Mar 1991
Lethal dosage ;
Respiratory system ;
Dose-response relationships ;
Lympoid tissue ;
Laboratory animals ;
Laboratory tests ;
US EPA ;
Union Carbide Chemicals and Plastics Company
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
The reports described a moderately high lethal inhalation toxicity of TMS to rats by exposure to vapor generated at ambient temperature. This was associated with severe injury and inflammation to the respiratory tract. The 1980 report was concerned with the effects of repeated exposures, and the 1988 supplemental report with an acute vapor exposure study. In order to more precisely define the concentration-response relationships for the known toxicity of TMS vapor, a short-term repeated vapor inhalation study is currently being conducted with rats. The information available to date confirms the lethal toxicity and respiratory tract injury.