Record Display for the EPA National Library Catalog


Main Title Concentration and Toxicity of Trifluralin in CD-1 Mice, Presented Intragastrically of Intraperitoneally.
Author Beck, Sidney L. ;
CORP Author Wheaton Coll., Norton, MA. Dept. of Biology.;Health Effects Research Lab., Research Triangle Park, NC.
Year Published 1978
Report Number EPA/600/J-78/185;
Stock Number PB81-232530
Additional Subjects Herbicides ; Toxicity ; Lethal dose ; Dosage ; Concentration(Composition) ; Mice ; Laboratory animals ; Ingestion(Biology) ; Parenteral infusions ; Reprints ; Trifluralin ; Toxic substances
Library Call Number Additional Info Location Last
NTIS  PB81-232530 Some EPA libraries have a fiche copy filed under the call number shown. 07/26/2022
Collation 9p
This report presents the results of experiments involving administration of the herbicide Trifluralin, dissolved in corn oil, delivered at different concentrations for each dose, either by intragastric intubation or intraperitoneal injection. The investigations produced several surprising results. These included the fact that, in per ora administration there were clear cut differences in toxicity such that for each dose which did cause death, there was inverse relationship between toxicity and concentration. This relationship was not seen in the intraperitoneal treatment groups. Further, there was no apparent difference in LD-50 in the two routes, and the time to death was greater in the intraperitoneally treated animals.