| Main Title |
Health assessment document for trichloroethylene : review draft / |
| Author |
Davidson, I. W. F. ;
Greenberg, Mark M. ;
Parker, Jean C.
|
| Other Authors |
|
| CORP Author |
Environmental Protection Agency, Research Triangle Park, NC. Environmental Criteria and Assessment Office. |
| Publisher |
U.S. Environmental Protection Agency, Office of Research and Development, Environmental Criteria and Assessment Office, |
| Year Published |
1982 |
| Report Number |
EPA-600/8-82-006 |
| Stock Number |
PB83-135970 |
| OCLC Number |
20601543 |
| Subjects |
Trichloroethylene
|
| Additional Subjects |
Toxicology ;
Industrial medicine ;
Exposure ;
Residues ;
Humans ;
Laboratory animals ;
Teratogens ;
Carcinogens ;
Physiological effects ;
Ethylene/trichloro ;
Air pollution effects(Humans) ;
Occupational safety and health ;
Toxic substances
|
| Internet Access |
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| EHAM |
EPA-600/8-82-006 |
|
Region 1 Library/Boston,MA |
05/25/2016 |
| EJAD |
EPA 600/8-82-006B |
|
Region 3 Library/Philadelphia, PA |
10/29/1993 |
DISPERSAL |
| EJED |
EPA 600/8-82-006 |
|
OCSPP Chemical Library/Washington,DC |
04/23/1999 |
| ELBD ARCHIVE |
EPA 600/8-82-006 |
Received from HQ |
AWBERC Library/Cincinnati,OH |
10/04/2023 |
| ESAD |
EPA 600-8-82-006 |
|
Region 10 Library/Seattle,WA |
07/29/2005 |
| NTIS |
PB83-135970 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
1 volume (various pagings) |
| Abstract |
Exposure to trichloroethylene is associated with neurological disorders, cardiovascular effects and damage to the liver and kidney. Liver and kidney damage have been attributed to chronic high exposure (>1.000 ppm). It is highly likely that the direct myocardial depressent effect, which is a serious health hazard for those with compromised or reduced cardiac reserve, occurs at lower exposure concentrations than has been previously thought. Although animal teratology studies performed to date are inconclusive, trichloroethylene could be teratogenic since: (1) it is distributed in the fetus, (2) biotransformation into reactive metabolites occurs in fetal liver, and (3) trichloroethylene has high lipid solubility. |
| Notes |
Includes bibliographical references. "EPA-600/8-82-006." "March 1982." "This document is a preliminary draft. It has not been formally released by EPA and should not at this stage be construed to represent Agency policy. It is being circulated for comment on its technical accuracy and policy implications." |
