||Health assessment document for trichloroethylene : external review draft.
Anderson, L. D. ;
Bayard, S. ;
Davidson, I. W. F. ;
Fowle, III, J. R. ;
Gibb, H. J.
||Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
|| U.S. Environmental Protection Agency, Office of Research and Development, Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office,
||EPA-600/8-82-006B; EPA-600/82-006B; EPA/600/B-82/006B
Trichloroethane--Toxicology--United States. ;
Air--Pollution--Physiological effect--United States. ;
Air--Pollution--United States--Physiological effect.
Industrial hygiene ;
Air pollution ;
Laboratory animals ;
Malignant neoplasms ;
Urban areas ;
Physical properties ;
Chemical properties ;
Transport properties ;
Occupational safety and health ;
Indoor air pollution ;
Toxic substances ;
Air pollution effects(Humans) ;
Path of pollutants ;
||Region 1 Library/Boston,MA
||Region 10 Library/Seattle,WA
||Some EPA libraries have a fiche copy filed under the call number shown.
||320 pages : illustrations ; 28 cm
Trichloroethylene (TCI) is a solvent widely used in the industrial degreasing of metals. It has been detected in the ambient air of a variety of urban and non-urban areas of the United States and also, in natural and municipal waters. The weight of available evidence obtained from both animal and human data suggest that long-term exposure to environmental levels of TCI poses no serious health concern to the general population. No teratogenic potential has been demonstrated for TCI in studies conducted to date with experimental animals. With respect to the mutagenic potential of TCI, the data on pure TCI do not allow a conclusion to be drawn. If TCI is mutagenic, the available data suggest it would be a very weak, indirect mutagen. Based on available animal cancer data, the classification of TCI under the criteria of the International Agency for Research on Cancer (IARC) could either be 'sufficient' or 'limited.' Because there are no adequate epidemiologic data, the overall ranking of TCI would place it in a category in which it would be a probable human carcinogen or one that cannot be classified as to its carcinogenicity.
December 1983. "EPA-600/8-82-006B. "Review Draft - Do not cite or quote." Includes bibliographical references.