||Initial Submission: Resistance to Listeria Monocytogenes Infection following a 34-Day Oral Toxicity Study of Tribuyyltin Oxide in the Rat with Cover Letter dated 09/29/1992.
||Hazleton Labs. America, Inc., Madison, WI.; Elf Atochem North America, Philadelphia, PA.; Environmental Protection Agency, Washington, DC. Office of Toxic Substances.
Health effects ;
Tributyltin oxide ;
CAS No 56-35-9
||Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy.
The objective of the study was to evaluate the immunotoxic effects of Bis (tri-n-butyltin) oxide (TBTO) using resistance to Listeria monocytogenes infection, following oral administration by admixture in the diet to the Sprague-Dawley rat for 34 days. The measurement of the clearance of the bacteria 4 days after the inoculation is an evaluation of cell-mediated immunity.