Record Display for the EPA National Library Catalog


OLS Field Name OLS Field Data
Main Title Quantification of Germ-Cell Risk Associated with the Induction of Heritable Translocations.
Author Dellarco, V. L. ; Rhomberg, L. R. ;
CORP Author Environmental Protection Agency, Washington, DC. Office of Health and Environmental Assessment.
Publisher c1990
Year Published 1990
Report Number EPA/600/J-93/208;
Stock Number PB93-199677
Additional Subjects Germ cells ; Translocation(Genetics) ; Mutagens ; Ethylene oxide ; Dose-response relationships ; Risk assessment ; Mice ; Humans ; Meiosis ; Species diversity ; Hereditary diseases ; Reprints ;
Library Call Number Additional Info Location Last
NTIS  PB93-199677 Most EPA libraries have a fiche copy filed under the call number shown. Check with individual libraries about paper copy. 08/23/1993
Collation 17p
The paper examines how quantitative risk methods might be extended to analyses of risks associated with the induction of heritable translocations in the human germ line. The chemical used in the modeling is ethylene oxide (EtO). It is hoped that this risk analysis will help define key types of data needed to quantify genetic risk, the biological considerations that go into such an analysis, and the inferences that must be drawn from mouse dose-response data when making predictions about human germ-cell risk. (Copyright (c) 1990. Cold Spring Harbor Laboratory Press.)