Record Display for the EPA National Library Catalog
RECORD NUMBER: 178 OF 416| Main Title | Experimental Studies on Chronic Poisoning of Rabbits with Low Concentrations of Chlorine and the Development of the Offspring of the Chlorine-Poisoned Rabbits (Experimentelle Studien ueber Chronische Vergiftung von Kaninchen mit Geringen Chlorkonzentrationen und die Entwicklung der Nachkommenschaft der Chlorvergiften Kaninchen). | |||||||||||
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| Author | Skljanskaja, R. M. ; Klaus, L. M. ; Ssidorowa., L. M. ; | |||||||||||
| CORP Author | Environmental Protection Agency, Research Triangle Park, N.C. Translation Services Section. | |||||||||||
| Year Published | 1935 | |||||||||||
| Report Number | EPA-TR-421-73; | |||||||||||
| Stock Number | PB-246 834-T | |||||||||||
| Additional Subjects | Chlorine ; Toxicology ; Poisons ; Rabbits ; Experimental data ; Embryos ; Translations ; West Germany ; Growth ; Reproduction(Biology) ; Industrial medicine ; Toxicity ; Pregnancy ; Laboratory animals ; Histology ; Pathology ; Exposure ; Body weight ; Bioassay ; Physiological effects ; Environmental health | |||||||||||
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| Collation | 19p | |||||||||||
| Abstract | Fifteen rabbits were subjected to chronic poisoning with low chlorine concentrations (0.002 - 0.005 mg Cl2 per liter air) for 1-9 months. In most of the experimental animals, significant weight losses and disorders of the respiratory organs which are characteristic of the action of chlorine were observed: catarrhalic changes of the upper respiratory tract, frequent metaplasia of the cylindrical epithelia of the bronchia into pavement epithelia, extensive centers of hemorrhages in the bronchi and lungs, lung emphysema and atelectases, and frequent infections diseases of the respiratory organs - pneumonias and pleuritises. Six chlorine-exposed rabbits showed a normal course of pregnancy and birth. The lactation period also took a normal course in these rabbits. Changes of the sex organs could not be detected in the chlorine-exposed rabbits. |