| Main Title |
Report of an Animal Experiment to Analyze Silica Gel Dust by Intratracheal and in Traperitoneal Injections in a Rat with Cover Letter dated 07/24/80. |
| CORP Author |
MCB Manufacturing Chemists, Inc., Cincinnati, OH.;Environmental Protection Agency, Washington, DC. Office of Toxic Substances. |
| Publisher |
30 Jul 1980 |
| Year Published |
1980 |
| Report Number |
8HEQ-0780-0354; |
| Stock Number |
OTS-0204857 |
| Additional Subjects |
Silica gel ;
Rats ;
Trachea ;
Dust ;
Quartz ;
Body weight ;
Toxicology ;
Pathology ;
Dosage ;
Silicosis ;
Laboratory animals ;
Lymph nodes ;
Heart ;
Liver ;
Spleen ;
Salts ;
Granuloma ;
Intramuscular injections ;
|
| Holdings |
| Library |
Call Number |
Additional Info |
Location |
Last
Modified |
Checkout
Status |
| NTIS |
OTS-0204857 |
Some EPA libraries have a fiche copy filed under the call number shown. |
|
07/26/2022 |
|
| Collation |
40p |
| Abstract |
The reaction and behavior of rats when injected with silica gel dust are being tested, as opposed to the reaction and behavior of a pure quartz dust application. For the experiment we used female Wistar rats weighing 250g. The animals were nourished with Altronium-R and water ad libitum. The dust originated from a fine dust sample from E. Merck, Darmstadt. The quartz was Doerentruper Nr. 12, sedimented to less than 3 micrograms. Both were suspended in a sterile 0.9 salt solution. The intratrachea injection contained a dust dose of 30mg/animal in 0.5ml salt solution-the intraperitoneum injections 50mg/animal in 1.0ml salt solution. |
